A Southern belle who's seemingly pure, virtuous, farm-girl sexy and city-woman sophisticated all at the... (Learn more)
Top Projects: Groundhog Day, Riding the Bus with..., Michael (View All)
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| Moved to Paris to work as an Elite model | |
| Worked at McDonald's while in high school | |
| 1978 | Dropped out of college at age 20 |
| 1978 | Moved to New York City |
| 1978 | Signed by Elite Model Managment |
| 1984 | Feature acting debut, "Greystoke: The Legend of Tarzan, Lord of the Apes"; played Jane; her natural Southern accent proved a problem and her dialogue was later dubbed by Glenn Close |
| 1985 | Feature acting debut with her own voice, "St. Elmo's Fire" |
| 1989 | Had breakthrough screen role in "sex, lies and videotape" |
| 1990 | Starred with Gerard Depardieu in the romantic comedy "Green Card" |
| 1991 | Played opposite Bruce Willis in the box-office bomb "Hudson Hawk" |
| 1991 | TV acting debut, "A Domestic Dilemma", a segment of HBO's "Women and Men II" |
| 1993 | Featured in the ensemble of Robert Altman's "Short Cuts" |
| 1993 | Played leading lady to Bill Murray in Harold Ramis' "Groundhog Day" |
| 1994 | Co-starred opposite Hugh Grant in the Oscar-nominated Best Picture "Four Weddings and a Funeral" |
| 1995 | Headlined Diane Keaton's "Unstrung Heroes" as a dying mother |
| 1996 | Appeared as a skeptical reporter who becomes romantically involved with William Hurt in "Michael" |
| 1996 | Portrayed Michael Keaton's wife in Ramis' "Multiplicity" |
| 1997 | Played Bill Pullman's wife in "The End of the Violence" |
| 1998 | Starred in "Shadrach" with Harvey Keitel |
| 1999 | Executive produced and co-starred with Andy Garcia in the comedy "Just the Ticket" |
| 1999 | Played the wife of blocked screenwriter Albert Brooks in Brooks' "The Muse" |
| 1999 | Profiled in Lifetime's "Intimate Portrait: Andie MacDowell" |
| 1999 | Realized her dream of acting with Miss Piggy in "Muppets from Space" |
| 2001 | Co-starred in the HBO adaptation of the Pulitzer-winning play "Dinner With Friends" |
| 2001 | Had featured role as Warren Beatty's vivacious paramour in "Town & Country", which also reteamed her with Keaton |
| 2005 | Appeared in the comedy "Beauty Shop" starring Queen Latifah |
| 2005 | Co-starred with Rosie O'Donnell in the CBS movie "Riding the Bus With My Sister," based on the book about her characters challenging relationship with her developmentally disabled sibling; directed by Anjelica Huston |
| 2006 | Voiced Etta the Hen in the animated feature, "Barnyard" |
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