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Sweet Surrender

Episode 20 | Season 5  (2008-2009)
(Airdate Apr 23, 2009)

As she endures aggressive treatment for her cancer, Izzie throws herself into planning Derek and Meredith's wedding. Callie introduces Arizona as her girlfriend to her disapproving father. George excels in a trauma emergency when Alex freezes. Owen seeks help with his PTSD.

Guest Stars