House (2004-2008)

Actor Hugh Laurie explains what was appealing about the character of House.

David Shore explains how he developed the concept of the hostile doctor.

Bryan Singer thought that House could only be played by an American actor.

Robert Sean Leonard tells his audition story and reveals why he likes "House".

Actor Jesse Spencer talks about taking a gamble and flying in for an audition.

Hugh Laurie, and others discuss the challenge of medical vocabulary.

The cast of 'House' voice their wishes for their characters for the next season.

Creator/Executive Producer David Shore shares his favorite one-liner.

David Shore and Katie Jacobs discuss their decisions behind House's disability.

Seth MacFarlane and Alex Borstein discuss the jokes that don't make it.

House: Season One starring Lisa Edelstein, Hugh Laurie, Jesse Spencer, Jennifer Morrison, Robert Sean Leonard, Omar Epps

Hugh Laurie and Dave Matthews talk about playing a duet in an episode of House.

Dave Matthews talks about playing a character on the show "House".

Actor Stephen Fry speaks about his long time friend and colleague, "House" star Hugh Laurie.

House creator, David Shore, talks about Chi McBride's guest star role.

A patient calls a doctor "incredibly hot."

Dr. Foreman is re-hired by Dr. Cuddy.

More Eastern European-sounding name: Dudek or Volakis?

In a future dystopia, people will have numbers, not names.

Kumar goes to the hospital.

Meet your interviewer.

Just another total House geek fan.

House: Season Two starring Lisa Edelstein, Omar Epps, Robert Sean Leonard, Hugh Laurie

Creator/executive producer David Shore shares his favorite one-liner. Actors Hugh Laurie (Dr. Gregory House) and Jesse Spencer (Dr. Robert Chase) discuss the challenges of acting so often with the same people.

Executive producer Bryan Singer discusses his history working with foreign actors and how he thought that House could only be played by an American actor.

Actors Omar Epps (Dr. Foreman), Robert Sean Leonard (Dr. Wilson), Jennifer Morrison (Dr. Cameron), Jesse Spencer (Dr. Chase), Hugh Laurie (Dr. House), and Lisa Edelstein (Dr. Cuddy) voice their wishes for their characters for the next season.

Actor Hugh Laurie (Dr. Gregory House) recalls how he initially got involved with the show and explains what was appealing about the character of House.

Actor Robert Sean Leonard (Dr. James Wilson) tells his audition story and reveals why he likes House over other pilots he auditioned for around the same time.

Creator/executive producer David Shore and executive producer Katie Jacobs discuss their decisions behind House's disability, the Fox network's reaction to it, and what his handicap means.

Actor Jesse Spencer (Dr. Robert Chase) talks about taking a gamble and flying in for an audition. He discusses the idea of openly playing an Australian which is so rare on television.

Creator/Executive Producer David Shore explains how he developed the concept of the hostile doctor and the Sherlock Holmes correlation.

Cast members Hugh Laurie (Dr. Gregory House), Robert Sean Leonard (Dr. James Wilson), and Jennifer Morrison (Dr. Allison Cameron) discuss the challenge of acting on a show that uses a medical vocabulary.

Go behind the scenes on Hollywood 411 with TV Guide's TV's Sexiest Stars: Omar Epps and Olivia Wilde from HOUSE. Find out who likes the compliment and who thinks sexy is intelligent and compassionate.

The cast discusses some of the twists and turns coming up in season five.